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Search Results for " gh receptor "

Targets Recommended: Somatostatin

12

抑制剂 & 化合物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9692	Paltusotine	Somatostatin	GPCR/G Protein
	Paltusotine 是一种口服有效的，非肽选择性生长抑素 2 型受体激动剂。在长效生长抑素受体配体作用后，Paltusotine 仍可维持 GH 和 IGF-1 水平。
TP1155L	Human growth hormone-releasing factor acetate	GHSR	GPCR/G Protein
	Human growth hormone-releasing factor acetate 是一种下丘脑多肽，通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。
T11798	L-692429 MK-0751	GHSR; GPCR19	GPCR/G Protein
	L-692429 (MK-0751) 是一种有效的非肽基生长激素促分泌素 (GHS) 激动剂，是一种苯并内酰胺的衍生物，可逆转糖皮质激素对 GH 分泌的抑制。L-692429 对 G 蛋白偶联受体 (G protein-coupled receptor)具有很高的亲和力，可用于研究肢端肥大症和肥胖。
T7112	Ibutamoren Mesylate MK-0677,伊布莫仑甲磺酸盐,MK-677	GHSR	GPCR/G Protein
	Ibutamoren Mesylate (MK-0677) 是非肽段类生长激素促分泌素受体 (GHSR) 激动剂，也是一种口服有活性的生长激素 (GH) 促分泌素。
TP2420	Veldoreotide DG 3173,DG3173,PTR 3173,DG-3173,Somatoprim
	Veldoreotide, also known as Somatoprim, is a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue which effectively reduces GH secretion in human GH-secreting pituitary adenomas, even in Octreotide non-responsive tumours.
T68276	Macimorelin acetate EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate
	Macimorelin (EP-1572) acetate，一种 GH 促分泌素，是一种具有口服活性的GHSR 激动剂。Macimorelin acetate 可刺激 GH 的释放。Macimorelin acetate 可用于成人生长激素缺乏症 (AGHD) 和癌症厌食-恶病质综合征 (CACS) 的研究。
T75157L	Cimdelirsen sodium
	Cimdelirsen (sodium) 为针对肝脏的反义寡核苷酸，通过减少生长激素受体(GHr)合成，抑制生长激素(GH)的过度分泌效应，进而降低肢端肥大症患者体内循环胰岛素样生长因子-1 (IGF-1)水平。
TP1155	Human growth hormone-releasing factor Growth Hormone Releasing Factor human
	Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothalamus. The main role of growth hormo
TP2032	des-Gln14-Ghrelin des-Gln14-Ghrelin (rat)
	An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH release in vivo.
T75157	Cimdelirsen
	Cimdelirsen为针对肝脏的反义寡核苷酸，通过降低生长激素受体(GHr)的合成量，来减少生长激素(GH)过量分泌所导致的不良影响，进而在肢端肥大症患者中降低循环胰岛素样生长因子-1(IGF-1)的水平。
T75713	Human growth hormone-releasing factor TFA
	Growth Hormone Releasing Factor human TFA 是下丘脑多肽，通过与GHRHR结合，刺激生长激素生成和释放。
TP1532	γ-2-MSH (41-58), amide
	Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to

化合物

Cat.No: T9692

Target: Somatostatin

Human growth hormone-releasing factor acetate

Cat.No: TP1155L

Target: GHSR

Cat.No: T11798

Synonym: MK-0751

Target: GHSR, GPCR19

Ibutamoren Mesylate

Cat.No: T7112

Synonym: MK-0677,伊布莫仑甲磺酸盐,MK-677

Target: GHSR

Cat.No: TP2420

Synonym: DG 3173,DG3173,PTR 3173,DG-3173,Somatoprim

Macimorelin acetate

Cat.No: T68276

Synonym: EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate

Cimdelirsen sodium

Cat.No: T75157L

Human growth hormone-releasing factor

Cat.No: TP1155

Synonym: Growth Hormone Releasing Factor human

des-Gln14-Ghrelin

Cat.No: TP2032

Synonym: des-Gln14-Ghrelin (rat)

Cat.No: T75157

Human growth hormone-releasing factor TFA

Cat.No: T75713

γ-2-MSH (41-58), amide

Cat.No: TP1532

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00806	GHR/Growth Hormone R Protein, Human, Recombinant (His) GHR/BP,GH receptor,GHBP,...	Human	HEK293 Cells
	Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
TMPJ-00356	GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) GHBP,GHR,Somatotropin receptor,gr...	Mouse	HEK293 Cells
	Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead...
TMPH-03683	Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) is expressed in E...
TMPH-03204	GHR Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941.
TMPH-03682	Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc) is expressed in E...
TMPH-01194	Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)	HHV-5	E. coli
	Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37....
TMPH-03112	GHR Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Pig, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P19756.
TMPH-02440	GHR Protein, Rhesus macaque, Recombinant (His)	Rhesus	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.2 kDa and the accession number is P79194.
TMPY-00186	GHRH Protein, Human, Recombinant (hFc) GRF,INN,growth hormone releasing hormone,GHRF	Human	HEK293 Cells
	The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl...

重组蛋白

GHR/Growth Hormone R Protein, Human, Recombinant (His)

Cat.No: TMPK-00806

Species: Human

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00356

Species: Mouse

Expression System: HEK293 Cells

Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)

Cat.No: TMPH-03683

Species: HHV-3

Expression System: E. coli

GHR Protein, Rabbit, Recombinant (His & Myc)

Cat.No: TMPH-03204

Species: Rabbit

Expression System: E. coli

Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc)

Cat.No: TMPH-03682

Species: HHV-3

Expression System: E. coli

Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)

Cat.No: TMPH-01194

Species: HHV-5

Expression System: E. coli

GHR Protein, Pig, Recombinant (His)

Cat.No: TMPH-03112

Species: Sus scrofa (Pig)

Expression System: E. coli

GHR Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPH-02440

Species: Rhesus

Expression System: E. coli

GHRH Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00186

Species: Human

Expression System: HEK293 Cells

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